KEGG   Mus musculus (house mouse): 77337
Entry
77337             CDS       T01002                                 
Symbol
Akr1c21, 9430025F20Rik
Name
(RefSeq) aldo-keto reductase family 1, member C21
  KO
K00212  20alpha/3alpha-hydroxysteroid dehydrogenase / dihydrodiol dehydrogenase [EC:1.1.1.149 1.1.1.357 1.3.1.20]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00140  Steroid hormone biosynthesis
mmu00980  Metabolism of xenobiotics by cytochrome P450
mmu01100  Metabolic pathways
mmu05208  Chemical carcinogenesis - reactive oxygen species
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    77337 (Akr1c21)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    77337 (Akr1c21)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    77337 (Akr1c21)
Enzymes [BR:mmu01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.149  20alpha-hydroxysteroid dehydrogenase
     77337 (Akr1c21)
    1.1.1.357  3alpha-hydroxysteroid 3-dehydrogenase
     77337 (Akr1c21)
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.20  trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
     77337 (Akr1c21)
SSDB
Motif
Pfam: Aldo_ket_red
Other DBs
NCBI-GeneID: 77337
NCBI-ProteinID: NP_084177
MGI: 1924587
Ensembl: ENSMUSG00000021207
UniProt: Q91WR5
Structure
Position
13:4624074..4636542
AA seq 323 aa
MNSKCHCVILNDGNFIPVLGFGTALPLECPKSKAKELTKIAIDAGFHHFDSASVYNTEDH
VGEAIRSKIADGTVRREDIFYTSKVWCTSLHPELVRASLERSLQKLQFDYVDLYLIHYPM
ALKPGEENFPVDEHGKLIFDRVDLCATWEAMEKCKDAGLTKSIGVSNFNYRQLEMILNKP
GLKYKPVCNQVECHPYLNQMKLLDFCKSKDIVLVAYGVLGTQRYGGWVDQNSPVLLDEPV
LGSMAKKYNRTPALIALRYQLQRGIVVLNTSLKEERIKENMQVFEFQLSSEDMKVLDGLN
RNMRYIPAAIFKGHPNWPFLDEY
NT seq 972 nt   +upstreamnt  +downstreamnt
atgaactccaaatgtcattgtgtcatattgaatgatggtaacttcattccagtgctgggt
tttggtactgctcttcctctagagtgtcccaagagtaaagctaaggagctcaccaaaata
gctatagatgctggtttccatcactttgattctgcttctgtctataatactgaagatcat
gtaggagaggccatcagaagcaagattgctgatggcactgtaaggagagaagatatattt
tacacctcaaaggtttggtgtactagccttcacccagaacttgtgagagcttccttggaa
cggtcactgcaaaaacttcagttcgactatgtggacctgtatctcattcattacccaatg
gccctgaaaccaggagaagaaaattttccagtagatgaacatggaaaattaatatttgac
agagtggacctctgtgccacctgggaggccatggagaagtgtaaggatgcaggactaacc
aagtccattggggtgtctaactttaactatagacagttggagatgattctgaataagcct
gggctcaagtacaagccggtatgcaaccaggtagaatgccatccttatctcaaccaaatg
aaacttctggatttctgcaaatcaaaagatattgtattggttgcctatggtgttctagga
acacaacgatatggaggatgggtagaccagaattcccctgttctcttggatgaaccagtt
cttggttccatggcaaaaaaatataatcgaactccagccttgattgcccttcgctaccag
ttacagcgtgggattgtggtcctcaacaccagtctcaaagaggagcggatcaaagagaac
atgcaggtttttgaattccagctgagttcagaggatatgaaagttcttgatggcctgaac
agaaatatgcgatacatacctgctgccattttcaagggccaccctaattggccatttttg
gatgaatactag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (17)   
   KEGG COMPOUND (17)   
Chemical reaction (10)   
   KEGG ENZYME (3)   
   KEGG REACTION (7)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (19)   
   RefSeq(nuc) (1)   
   GenBank (9)   
   EMBL (9)   
3D Structure (8)   
   PDB (8)   
Protein domain (1)   
   Pfam (1)   
All databases (77)   

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